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Platelet-poor plasma : ウィキペディア英語版 | Platelet-poor plasma Platelet-Poor Plasma (PPP) is blood plasma with very low number of platelets (< 10 X 103/μL). Traditionally, PPP was recommended for use in platelet aggregation studies to both adjust the Platelet-rich plasma concentration, and to serve as a control.〔Marco Cattaneo, Anna Lecchi, Maddalena Loredana Zighetti, Federico Lussana. "Platelet aggregation studies: autologous platelet-poor plasma inhibits platelet aggregation when added to platelet-rich plasma to normalize platelet count". Haematologica, 2007, 92(05)〕 PPP may have elevated levels of fibrinogen, which has the ability to form a fibrin-rich clot once activated. Wound healing requires cell migration and attachment, which is facilitated by this fibrin clot.〔Richard A.F. Clark. "Fibrin and Wound Healing". Annals New York Academy of Sciences, 2001, vol. 936 pp. 355–367.〕 ==Current Uses== Fibrin sealants have found use in many clinical situations such as blood management,〔R.K. Spence. "Current concepts in Blood Management". Orthopaedics, 2004;27:S643-S641〕 orthopaedic surgery,〔R. Justin Thomas, Scott E. Marwin. "The role of fibrin sealants in orthopaedic surgery". Journal of the American Academy of Orthopaedic Surgeons, 2009, Vol 17, No 12.〕 and cosmetic surgery.〔Man, D., Plosker, H., Winland-Brown, J.E. "The use of autologous platelet-rich plasma (platelet gel) and autologous platelet poor plasma (fibrin glue) in cosmetic surgery". Plastic and Reconstructive Surgery, Vol 107, Issue 1, pp. 229–239〕
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Platelet-poor plasma」の詳細全文を読む
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